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Green Tea EGCG Health Advantage In Cardiovascular Disorder Controlling As our community is getting richer, people are more health understanding today. In term of drink, green tea is thought as the healthiest drink as it is not only has the rehydrate function, but it is also flavonoid rich that manage to guard our body against cardiovascular disease. Study on green tea drinkers illustrate that they are significantly less vulnerable to a wide range of illness, from viral infection to chronic degenerative ailment like stroke, cancer, cardiovascular disease and osteoporosis. Research illustrates that green tea has extremely high level of flavonoids (antioxidant) including catechins and their derivatives. Antioxidant is the biological process that curbs the oxidation which will produce highly reactive free radicals. Flavonoids substance consists of more than 30% of the green tea dry weight. Epigallocatechin-3-gallate (EGCG) is the largest prolific catechin in all green tea. It has the greatest antioxidant activity of all green tea's catechins and therefore is believed to act the most significant role in the green tea's anticancer and antioxidant effect. Green tea EGCG is so abundant that a cup of green tea can have 20-35mg of it. In our arteries, there is a one cell thick lining that acts as the boundary layer between the bloodstream and the wall of the artery where blood plaques may form, this is known as arterial endothelium. When cardiovascular disease occurs, a kind of enzyme will hasten the production of free radicals in the artery endothelium, thus boosts the level of free radicals in arteries abruptly. Green tea EGCG will inhibit the enzymes needed in the fabrication of the free radicals and thus shields the endothelium from injured by free radical. Hence green tea is playing a critical role in preventing cardiovascular disease. EGCG also helps in curbing the death of heart muscle cells following ischemia/reperfusion injury, by obstructing the stimulation of inflammation compounds (STAT-1) that will induce oxidative damage which kills heart cell in reperfusion injury. Besides, cancer cells need enzyme dihydrofolate reductase (DHFR) to compose DNA and multiply. EGCG will inhibit the DHFR and is practically obstructing the spread of cancer cells. Furthermore, EGCG could also speed up the salvage of damaged heart cells, and accordingly allowing quick recovery of tissues and remedying organs injury. In conclusion, green tea EGCG has wonderful benefit in helping heart disease controlling as well as in heart disease damage healing. As such for those who are suffering from heart disease and those who are health conscious, green tea is the best option of beverage for them. Having few cups of green tea, primarily decaf green tea a day rather than decaffeinated coffee will definitely guarantee our long term health. 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